产品货号：
Z24157
中文名称：
PSD95/DLG4抗体
英文名称：
Anti-PSD95/DLG4 Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-PSD95/DLG4 Antibody |
| 指标别名 | Disks large homolog 4;DLG4;PSD 95;PSD95;PSD95-Specific;DLG4;SAP 90;SAP90;Synapse associated protein 90 |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | WB,IHC,IF |
| 基因名称 | DLG4 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | A synthetic peptide corresponding to a sequence at the C-terminus of human PSD95(492-507aa RRVERREWSRLKAKDW),identical to the related rat and mouse sequences. |
| 实际分子量 | 95～100KD |
| 成分 | 500μg/mL antibody with PBS，0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | Immunogen affinity purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | DLG4 discs large homolog 4,also known as PSD95 or SAP-90,is a protein that in humans is encoded by the DLG4 gene.It is a member of the membrane-associated guanylate kinase(MAGUK) family.This gene is mapped to 17p13.1.DLG4 can heteromultimerize with another MAGUK protein,DLG2,and is recruited into NMDA receptor and potassium channel clusters.These two MAGUK proteins may interact at postsynaptic sites to form a multimeric scaffold for the clustering of receptors,ion channels,and associated signaling proteins.Overexpression of DLG4 in hippocampal neurons could drive maturation of glutamatergic synapses.DLG4 can orchestrate synaptic development and it has a role in synapse stabilization and plasticity.Ubiquitination of DLG4 through an MDM2-mediated pathway can regulate AMPA receptor surface expression during synaptic plasticity. |
| Uniprot ID | P78352 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P).*Blocking peptide可以联系我们购买。 |
| 基因名全称 | discs,large homolog 4(Drosophila) |
| 蛋白名全称 | Disks large homolog 4 |
| 推荐稀释比 | Western blot (WB) 1:500～2000 Immunohistochemistry in paraffin section (IHC) 1:50～400 Immunofluorescence (IF) 1:50～400 (Boiling the paraffin sections in 10mM citrate buffer,pH6.0,or PH8.0 EDTA repair liquid for 20 mins is required for the staining of formalin/paraffin sections.) Optimal working dilutions must be determined by end user. |
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